Pseudoscience: IgG Food Intolerance Tests
William Thompson, the Savannah, Georgia Daily Morning News editor who designed the Confederate flag describes its racist meaning
What the rich want, everyone in the US gets. Survey data
Making Leavers machine lace
Why early Chlamydia vaccines failed (and lowered resistance to Chlamydia)
RepSox, a TGF-β1 inhibitor, promotes stem cell growth and enhances neurogenesis and muscle regeneration in old mice. Neurogenesis occurs primarily in the dentate gyrus of the hippocampus, and this is where the authors find it. No functional tests are shown.
The compound, 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine or RepSox (PubChem) has been mentioned in half a dozen studies as a drug that promotes stem cell proliferation. Compound sells for research use at $50 / gram.
<p>Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal. Hanadie Yousef, Michael J. Conboy, Adam Morgenthaler, Christina Schlesinger, Lukasz Bugaj, Preeti Paliwal, Christopher Greer, Irina M. Conboy, David Schaffer
Oncotarget. May 06, 2015. (pdf)
Bad batteries–vaccum has 13 sub C NiCD cells. Tested voltage on the individual cells and replaced 6 bad cells.
The vaccum still wouldn’t charge–checking the charging circuit board showed a crack in a trace near the edge where the indicator LED is located. A bit of solder fixed it, and now it is charging.
FYI, the main IC on the circuit board is a ABOV MC96P0202, a 8-bit OTP CPU.
Recently Gao et. al. published “An Estimate of the Average Number of Recessive Lethal Mutations Carried by Humans”. They studied a Hutterite group in South Dakota, highly inbred (63 founders 13 generations ago). From serious genetic diseases common in this population, they determine the number of deleterious variants present in the founders. They find that 0.29 recessive lethal alleles per haploid genome. Since some lethals manifest before birth, they double the estimate to 0.58.
This gives an expected 1.8% increased chance of a genetic disease from two first cousins.
Gao, Z., Waggoner, D., Stephens, M., Ober, C. & Przeworski, M. Genetics 199, 1243–1254 (2015).
NPR Enables The Anti-Worker Movement
Economics blog: Beat the Press (Dean Baker)
Purple frog
Ultrasound Alzheimer’s treatment fully restores memory function. pub link. Worth following up in a year
Welfare that the well off get
Medzhitov / Galli theory that allergies are a response to toxic chemicals
Family firms
Survey of gun researchers: having a gun increases your risk
Ending the Creditor’s Paradise
First detailed microscopy evidence of bacteria at the lower size limit of life (0.2 um, 1/150th size of an E. coli) (paper)
Best Feminist Books For Younger Readers
Cold-brewed chocolate
A Chladni plate experiment–visualizes complex resonance patterns
Fuse glass in a microwave and metals
Variant annotation: ANNOVAR vs VEP: McCarthy et. al., 2014, pdf, suppl.
Blog post with a comparison: State of Variant Annotation: A Comparison of AnnoVar, snpEff and VEP by Andrew Jesaitis
TIP – Troubles in Paradise (history of creationist argumentation)
The Irrationality of Alcoholics Anonymous–using naltrexone to treat alcoholism
Krugman reports on the Republican budget proposal
A Scientist’s Guide to Citizen Science
Comic: Phoebe and Her Unicorn
Illumina sequencer comparison: XTen, HiSeq 2500, NextSeq 500, MiSeq
NextSeq 500, an odd choice
How fast is your flash? Measuring high-speed flashes
Plans for an air-gap flash
The Infection Schedule versus the Vaccination Schedule by Mark Crislip. Comparing the antigens in a vaccine to the number a person responds to in ordinary life.
Elysium Health (Guarente) has a NAD precursor + sirulin targeting anti-oxidant, $2/day
VAX! A game about epidemic prevention.
Roald Dahl on Olivia, writing in 1988. “MEASLES: A dangerous illness.”
UPC codes for a product, inexpensive from a reseller
USB id for a product, inexpensive from a reseller
I was sent a link to a blog post, “This Mama Isn’t Scared of the Shmeasle Measles” by Megan Heimer.
I’ll run through the post in a minute, it contains a whole lot of nonsense. First, some links to reliable info:
CDC measles info
CDC Manual for Surveillance of VPD: Chapter 7: Measles
Measles week posts by an immunologist
Now, on to the post…
Designing The Best Board Game On The Planet: Twilight Struggle by Oliver Roeder
After 10 years, few payoffs from Gates’ ‘Grand Challenges’
the Mincome experiment in Dauphin, Manitoba, 19774-1979
State tax rates 2014
International SAT is Corrupt.
Great Commodore 64 game: The Castles of Dr. Creep (rewrite, description)
Science and the AAAS sell their souls to promote pseudoscience in medicine by Orac, link to Science advert Supplement
Bat hibernation, muted immune response, and aging
More Rotavirus Vaccination Means Less Rotavirus, paywalled article Sahni et al., 2015 in Pediatrics
Cooking charts
Pioneer Girl by Laura Ingalls Wilder review
